Having endometriosis and being 22 weeks pregnant will not usually affect the fetus. Endometriosis is a condition in which endometrial tissue grows outside of the uterine cavity and myometrium. The pathogenesis of endometriosis is unclear, and it is thought to be related to genetics, immunity, inflammation, and other factors, while higher estrogen levels and autoimmune diseases can increase the risk of endometriosis. And the chance of infertility in patients with this disease is as high as 40%. If the patient is clinically cured and becomes pregnant, there is usually no effect on the fetus or the pregnancy, and the pregnancy process can also reduce the risk of recurrence of the disease. In some cases, the disease can be reduced, so there is no need to worry too much. Pregnant women should take good care of themselves under the guidance of their doctors and take regular pregnancy tests to check the development of the fetus.