Numbness in women’s hands at night is often caused by nerve compression in a part of the upper extremity, causing nerve entrapment, commonly the median and ulnar nerves. Generally, the median nerve tends to form a compression in the palmar side of the wrist, called carpal tunnel syndrome, often manifesting as numbness in the thumb, index finger, and middle finger, which can be alleviated by shaking the hand, and pressure on the palmar side of the wrist may induce pain radiating to the fingers. Another nerve is the ulnar nerve, which is often compressed behind the elbow joint, called elbow canal syndrome, often causing numbness and hypesthesia in the little finger and ring finger on the side of the little finger, sleep with the elbow joint bent, easily induced numbness, try to straighten the elbow joint to relieve, numbness may be reduced, also need to do electromyography to confirm the diagnosis. If there is no effect, the numbness is not reduced, and even the muscle atrophy of the hand appears, surgery should be performed to decompress the tissue compressing the nerve, generally speaking, the effect is better after decompression of the median nerve, and recovery is very fast.