Itchy skin surface and nothing may be the result of mental stress, dry skin and other physiological factors, followed by diabetes, uremia and other diseases. 1. Physiological factors: nervousness, dry skin and other physiological factors may lead to itchy skin surface and nothing. 2. Diabetes: the formation of diabetes may be related to genetic, environmental and other factors, if the patient’s blood sugar continues to rise, may lead to complications, including itching, tingling and other symptoms. 3. Uremia: the cause of uremia may be related to disease, genetics and other factors, the patient’s skin will appear dry, itching and other symptoms. The cause of itchy skin surface and nothing is not the only reason, after excluding physiological factors, patients are advised to seek medical examination to clarify the cause of the disease.