Comatose patients with hydrocephalus can wake up with aggressive treatment. There are many causes of hydrocephalus, such as tumor, infection, cerebral infarction, traumatic brain injury, and hypoplasia of the median foramen or interventricular foramen. Treatment is mainly surgical to reduce intracranial pressure. Patients who are in coma should be treated for the cause of coma, and when accompanied by hydrocephalus, they should also actively cooperate with the doctor for treatment. After treatment, it is possible for the patient to wake up. Hydrocephalus is a condition in which cerebrospinal fluid accumulates excessively in the ventricular system and/or subarachnoid space due to overproduction of cerebrospinal fluid, obstruction of circulation, or obstruction of absorption caused by a variety of reasons, often accompanied by enlargement of the ventricles, a corresponding decrease in the brain parenchyma, and an increase in intracranial pressure.