Getting up in the morning with a bitter and smelly mouth may be dietary factors (consumption of indigestible or easy to produce a special flavor such as garlic, etc., need to adjust the dietary structure), or pathological factors (such as oral diseases, renal insufficiency, etc., need to be treated by specialists), need to be analyzed specifically. 1. Dietary factors: Eating foods that are easy to produce a special smell or not easy to digest before going to bed, such as garlic, onions, etc., and then waking up in the morning, there will be a bitter and smelly mouth, you can adjust your dietary structure to avoid or reduce the consumption of the above foods, or brush your teeth and rinse your mouth in a timely manner after eating them. 2. Pathological factors: oral diseases (such as dental caries, periodontitis, etc.), renal insufficiency and other diseases can lead to bitter and smelly mouth. Oral disease will also appear toothache, bleeding gums and other symptoms, need to pay attention to oral hygiene, after meals to brush, rinse in time, if necessary, stomatology specialist for treatment. Chronic renal insufficiency can also appear weakness, nausea and other symptoms, renal function and other tests can be clearly diagnosed, need to consult the nephrology department in time. Wake up in the morning, mouth bitter and odor of the etiology of many, may be a dietary problem, may also be caused by physical diseases, it is recommended to consult a doctor in a timely manner, a clear diagnosis.