Diarrhea after ursinumab injection is usually caused by adverse reactions, you can use antibiotics, diarrhea, probiotics and other drugs under the guidance of the doctor for treatment, but also need to replenish water in a timely manner, to prevent the emergence of symptoms of dehydration. 1. Use of antibiotics: you can follow the doctor’s instructions to choose ofloxacin capsules, cefmenoxime tablets, cefixime tablets and other drugs for treatment, can play a role in eliminating the role of pathogenic microorganisms in the gastrointestinal tract, the treatment of diarrhea has a better effect. 2. Cure diarrhea class: such as montelukast, etc., can play the role of astringent diarrhea, can better absorb the water in the gastrointestinal tract, relieve diarrhea. 3. Probiotics: patients can also use compound Lactobacillus acidophilus, lactobacillus tablets and other drugs under the guidance of the doctor, which is conducive to the regulation of intestinal flora, improve the intestinal micro-environment, and also has a better effect on the treatment of diarrhea. 4. Timely supplementation of water: because diarrhea may lead to symptoms of dehydration, so it is necessary to timely supplementation of water, and if the symptoms are more serious, it is also necessary to be treated through intravenous rehydration. After the injection of ustekinumab with diarrhea it is recommended to consult a doctor to give the correct treatment, do not blindly use drugs.