The swelling of one side of female labia majora is considered to be related to trauma, vestibular gland cyst, vestibular gland abscess, etc. The treatment should be based on the cause of the disease through anti-infective drugs or surgical treatment. 1. Trauma: due to the labia majora tissue is relatively loose and rich in blood vessels, the local role of external forces, easily lead to the formation of local hematoma, and then the patient will be conscious of the local formation of a painful mass, at this time you can use Yunnan Paiyao and other antiemetic drugs to treat the trauma is more serious need for surgical treatment. 2. Vestibular gland cysts: if the local combination of vulvovaginitis, vestibular gland ducts will be blocked, and then the local production of glandular fluid can not be discharged normally and silt in the local formation of retention cysts, if the cysts are relatively small can not be treated, if the cysts are larger, if necessary, need to be incised and drained. 3. Vestibular gland abscess: If there is bacterial infection on the basis of vestibular gland cyst, vestibular gland abscess will be formed, at this time, we need to use cephalosporin, penicillin and other antibiotic preparations for treatment, and when the abscess has a fluctuating sense of localization, it is necessary to make incision and drain pus in a timely manner. For women with enlarged labia, it is recommended that they go to the gynecology department of a regular hospital to get a clear picture of the cause of the problem and then actively treat it under the guidance of the doctor.