The causes of pain after removal of bile drainage tube include biliary stasis, local injury and other causes. 1. Biliary stasis: After the bile drainage tube is removed, the bile still cannot flow out smoothly, which will easily cause biliary stasis and cause pain. Secondly, some patients may have nausea and vomiting, loss of appetite. This is more common with bile duct stones. 2. Local injury: at the beginning of removing the bile drainage tube, the wound is not yet healed and accompanied by edema, which will cause pain and inconvenience to the patient’s life. 3. Local inflammation: If cholecystitis occurs in the gallbladder after the removal of the gallbladder puncture tube, it can lead to local pain. After removing the bile drainage tube, you should take good care of the patient to avoid infection that may affect the recovery process. If the symptoms persist for a long time, it is recommended to go to the hospital as soon as possible for examination and treatment under the guidance of healthcare professionals.