Leflunomide and glucuronolactone tablets can usually be taken at the same time, as directed by your doctor. Leflunomide is an immunosuppressant drug used in the treatment of rheumatoid arthritis (improvement of disease) and lupus nephritis in adults. It is contraindicated in people who are allergic to the product and its metabolites, and in patients with severe liver damage. Adverse drug reactions are mainly dizziness, headache, diarrhea, alopecia, rash, itching, elevated transaminases. Note that patients with severe immunodeficiency, bone marrow dysplasia and other patients should not use this product. Glucuronolactone Tablet is a kind of auxiliary therapeutic drug for liver disease, which has the effects of protecting the liver and detoxification, and is suitable for the auxiliary treatment of acute and chronic hepatitis. It should be contraindicated for those who are allergic to this product. Occasionally, there are adverse reactions of redness and mild gastrointestinal discomfort, which may disappear by reducing the dosage or stopping the use of the drug. In case of overdose or serious adverse reactions, seek immediate medical attention. Leflunomide and glucuronolactone tablets generally do not have drug interactions, in addition to leflunomide has hepatotoxicity, while glucuronolactone tablets happen to have hepatoprotective and detoxification effects, so at the same time meet the indications of the two, can be taken at the same time, but the specific use of drugs should be carried out under the guidance of a specialist.