Rivaroxaban should not be taken during menstruation and its use should be directed by a doctor. Rivaroxaban is an antithrombotic drug that is used to prevent venous thrombosis, treat deep vein thrombosis in adults, and reduce the risk of stroke and systemic embolism. Taking rivaroxaban carries the risk of bleeding, as the body is already bleeding during menstruation, and taking rivaroxaban can increase the bleeding, which can then lead to shock and other dangers due to excessive bleeding. Additionally taking rivaroxaban may bring about adverse reactions such as abdominal pain, toothache, indigestion, headache, and blood clotting abnormalities. Rivaroxaban is contraindicated for those who are allergic to rivaroxaban and its excipients, those who have obvious active bleeding, pregnant and lactating women, and those with coagulation disorders. In order to reduce rivaroxaban adverse reactions and avoid the harm caused by the drug to the body, taking rivaroxaban should be done under the supervision of a doctor.