Headache, sore throat and a little fever are mostly caused by cold and tonsillitis, which can be treated with anti-flu drugs, analgesic and antipyretic drugs or antibiotics. 1. Cold and flu: the first consideration is the initial symptoms of wind-heat cold and flu, you can take blue scutellaria oral liquid, Lianhua Qingdian capsule, etc., and closely observe the patient’s condition. 2. Tonsillitis: this disease will also appear headache, sore throat fever, etc., mainly take antibiotic drugs for treatment, such as penicillin, azithromycin drugs, during the period of time need to maintain oral hygiene, drink more warm water. Appearance of the above symptoms, especially when there is fever, it is recommended to timely hospital consultation, under the guidance of the doctor standardized treatment, not blindly use drugs. The above drugs need to be standardized and rationally applied under the guidance of professional physicians and pharmacists.