Clinical COPD specific medication is as follows: 1, stable period: usually choose beta agonists, anticholinergic receptors, inhaled hormones three preparations alone or combined. If the inhaled preparation can no longer relieve the patient’s symptoms, oral roflumilast drugs can be appropriate, and if the patient is a long-term smoker, macrolides can be taken in moderation under the guidance of the doctor; 2. Acute exacerbation: if the patient has an indication to use antibiotics, antibiotics can be applied in a timely manner to treat the patient, such as inhaled short-acting β agonists or anticholinergic drugs. In addition, hormones can also be taken orally or intravenously, but long-term use is not recommended, usually 5-7 days to stop.