Lacrimal gland, sweat gland and salivary glands first increase and then reduce the secretion of neurological food poisoning (botulism), the vegetative nerve endings are first excited and then inhibited, so the lacrimal glands, sweat glands and salivary glands first increase the secretion and then reduce it. Due to the weakness of the neck muscles, the head is tilted forward to one side. During the course of the disease, the consciousness is clear, the sensation is normal, and there is no fever. It is often accompanied by constipation, abdominal distension and urinary retention. Mild cases gradually recover within 5-9 days, but generalized weakness and paralysis of eye muscles last longer. Most of the deaths are caused by untimely resuscitation in severe cases, with a case fatality rate of 30% to 60%, and the causes of death are mostly respiratory failure due to medulla oblongata, cardiac insufficiency and secondary infections due to aspiration of pneumonia. The first symptom of infant patients is often constipation, rapid cranial nerve paralysis, can be due to sudden central respiratory failure and sudden death (sudden infant death syndrome SIDS). Lacrimal sweat glands and salivary glands and other secretion first increased and then reduced the onset of sudden illness, the disease can be headache, dizziness, vertigo, fatigue, nausea, vomiting (E bacteria nausea and vomiting heavy, A bacteria and B bacteria is lighter); later, the internal and external ophthalmic muscle paralysis, the emergence of ophthalmic symptoms, such as blurred vision, diplopia, eyelid ptosis, pupil dilatation, the disappearance of the light reflex. The mouth and pharynx are flushed with sore throat, and dyspnea occurs if the pharyngeal muscles are paralyzed. Low muscle strength is mainly seen in the neck and proximal limbs. The head is tilted forward or to one side due to weakness of the neck muscles. Tendon reflexes may be symmetrically diminished. Lacrimal sweat glands and salivary glands, etc. first increase secretion and then reduce how to effectively prevent and treat it? 1, in daily life, pay more attention to rest. In the diet, more light food. 2.Anti-toxin treatment. Polyvalent botulinum toxin (A, B, E type) has special effect on this disease, must be applied early. 3, Symptomatic treatment. Patients should be strictly bed rest, and appropriate sedation to avoid aggravation of paralysis. Patients can be used 5% sodium bicarbonate or 1:4000 potassium permanganate solution for gastric lavage and enema within 4h after eating, in order to destroy the toxins that have not been absorbed in the stomach and intestines. 4.Chemotherapy.