Gastric quadruple therapy includes a proton pump inhibitor, a proton pump inhibitor and two antibiotics. No contraindications have been found to the use of the above medications with Fenofibrate, so they can be taken together, and the intervals generally do not need to be too long. Gastric quadruple therapy generally refers to the combination of proton pump inhibitors such as omeprazole, bismuth agents such as bismuth potassium citrate, and two antibiotics such as metronidazole and clarithromycin, which is used for the eradication of Helicobacter pylori. The medication should be taken continuously. Due to the effect of bismuth, it is possible that the stool may appear black. It is recommended to use it under the guidance of a medical professional. Fenofibrate is a lipid-regulating drug generally used for the treatment of hyperlipidemia in adults with poor dietary control, and its triglyceride-lowering and mixed hyperlipidemia effects are more pronounced than those of cholesterol. Occasionally, there are adverse reactions such as dry mouth, loss of appetite, increased frequency of bowel movements, rash, abdominal distension and leukopenia; contraindicated in pregnant women; used with caution in patients with hepatic and renal insufficiency. The above drugs should be used under the guidance of a professional physician to avoid adverse effects.