The feeling of insects crawling and ants biting in the shoulder joint may be caused by autonomic nerve disorder, or it may be caused by cervical spondylosis or diabetes mellitus. 1. Autonomic disorders: The feeling of insects crawling and ants biting in the shoulder joint may be caused by autonomic disorders. It is recommended to have a reasonable work and rest, appropriate exercise, relaxation, avoid excessive stress, and if necessary, supplement vitamin B for treatment. 2. Cervical spondylosis: Patients with cervical spondylosis may have peripheral nerve sensory impairment in the shoulder, accompanied by stiffness in the neck, dizziness and other symptoms. It is recommended that patients choose drugs for treatment (such as diazepam) under the guidance of doctors. For patients whose medication is not obvious or ineffective, surgery may be considered as an option. 3. Diabetes mellitus: Diabetes mellitus can be caused by heredity, environmental factors, etc. It can appear with symptoms characterized by excessive drinking, urination, and eating, and weight loss, in addition to itchy skin sensation, neuropathy, etc. It is recommended to monitor blood glucose, control blood sugar, and control blood pressure. It is recommended to monitor blood glucose, control blood glucose, reasonable diet and appropriate exercise. Patients who have the feeling of insect crawling and ant biting in the shoulder joint need to go to the hospital for appropriate examination to confirm the diagnosis, and carry out specific treatment for different causes.