Patients with bone cold pain symptoms, the following reasons are common: 1, osteoarthritis: mainly related to degenerative changes, joint blood circulation disorders and manifested as synovial inflammation, the patient will have symptoms of bone pain, accompanied by chills, generally accompanied by joint stiffness, the range of joint activities will be significantly reduced, X-ray film will find joint degeneration, osteophytes, joint space narrowing, the patient 2, lower extremity arterial stenosis: such as lower extremity plaque formation, can cause blood vessel lumen narrowing, insufficient arterial blood supply will cause lower extremity bone head cold pain clinical symptoms, insufficient blood supply will stimulate the nerves, causing pain symptoms continue to aggravate, and skin temperature will continue to decrease, through the vascular ultrasound examination can find the location of the lesion and the extent of the lesion.