The causes of yellowing of white eyeballs are physiological and pathological, which may be the precursor of viral hepatitis and obstructive jaundice, and the treatments include medication such as antiviral drugs and surgery. 1. Physiological factors: with the growth of age, the organs of human body gradually degenerate and weaken gradually, the white eyeballs will gradually become yellow, which is a normal physiological phenomenon. This is a normal physiological phenomenon. Excessive use of the eyes, staying up late and not enough rest, obesity and other factors can also lead to yellowing of the eyeballs, and develop good habits of work and rest, and actively exercise can effectively alleviate the symptoms. 2. Pathological factors (1) Viral hepatitis: symptoms such as jaundice, nausea and vomiting. Medications include dalatavir, entecavir, etc. Liver transplantation is feasible when the condition is serious. (2) Obstructive jaundice caused by bile duct obstruction: manifested by yellowing of sclera, chills and fever, treatment includes medication such as magnesium sulfate, ursodeoxycholic acid, etc. Surgery such as cholecystectomy is practiced according to the condition. Yellowing of the white eyeballs, accompanied by other discomforts, should go to the hospital as soon as possible.