Vulvar leukoplakia is generally not curable. Vulvar leukoplakia is an autoimmune disease, and the underlying cause and mechanism are not completely clear, so there is no way to completely cure it at present. Patients with vulvar leukoplakia may show itching, dry, thickened and whitened skin, loss of elasticity, and in severe cases, vulvar atrophy, ulceration, burning, and accompanying pain. Certain treatments for vulvar leukoplakia can be taken to slow down the progression of the disease, and regular annual checkups are needed to rule out more serious lesions. Vulvar leukoplakia can be treated with hormonal ointments, such as testosterone propionate ointment and mometasone furoate, as well as physical therapy, such as microwave, Bohm light, carbon dioxide laser, and surgical procedures, such as simple vulvovaginal excision or vulvovaginal excision with skin grafting, if necessary. Although vulvar leukoplakia cannot be cured, it is necessary to go to the hospital for targeted treatment to alleviate the symptoms.