Colchicine and allopurinol tablets are not recommended to be taken at the same time during gout attack. Colchicine tablets for gout acute attack patients with joint swelling, severe joint pain and other symptoms with obvious relief, is currently the first-line gout acute attack treatment, allopurinol tablets is a kind of inhibition of uric acid synthesis to reduce the level of uric acid in patients with medication, gout attack is not recommended to take allopurinol and other uric acid-lowering drugs. It is generally recommended that gout attacks end at least 2-4 weeks before starting uric acid lowering treatment, because patients taking allopurinol can prompt uric acid crystals to re-dissolve resulting in fluctuations in the level of uric acid in the body and may therefore cause the patient arthritis symptoms worsen. Colchicine tablets and allopurinol tablets should be used under the guidance of a physician, it is recommended that patients to the rheumatology and immunology department of the regular hospital and other related departments for detailed consultation, follow the doctor’s instructions standardized medication.