Whether hormone dosage reduction can lead to a decrease in white blood cells cannot be generalized. If the increase in white blood cells is caused by the long-term use of hormone drugs, then hormone use is gradually reduced, and white blood cells can be lowered accordingly; if the increase in white blood cells is caused by other reasons, which have nothing to do with the use of hormones, the primary disease needs to be treated, and the hormone reduction is ineffective. Long-term use of hormonal drugs can lead to changes in the distribution of white blood cells in the blood, the total number of white blood cells and neutrophils is high, while the total number of lymphocytes is low. If the increase in white blood cells is caused by the use of hormones, the total number of white blood cells will gradually decrease to the normal range when the condition requires a gradual reduction in hormone dosage. If the increase in white blood cells is not related to the use of hormones, then even if the amount of hormones is reduced, the white blood cells will not decrease. When patients taking hormone drugs, do the examination suggests that the white blood cell increase, should promptly ask the doctor, under the guidance of the doctor for treatment, not blindly reduce the amount of hormone.