Gastric fundus submucosal bulge is a gastroscopic manifestation, the causes of gastric fundus submucosal bulge may be gastric mesenchymal tumor, gastric smooth muscle tumor, gastric lipoma, gastric venous tumor, and may be caused by ectopic pancreas or peripheral organ compression. According to the pathological results, in the case of benign tumors, regular rechecking of gastroscopy is recommended between 6 months and one year, and gastric smooth muscle tumors are recommended to be promptly resected and treated. The causes of these diseases are closely related to the environment and genes. In differential diagnosis, what is the cause is diagnosed according to the mobility of the bulge, the state of the mucosa, the size and other factors, and ultrasound endoscopy and tissue biopsy can be done to help diagnosis if necessary. If it is gastric mesenchymal tumor, gastric lipoma, etc., gastroscopic resection is generally recommended for treatment. If it is a benign tumor, regular review of gastroscopy every six months or one year can be sufficient.