The treatments for lupus nephritis type 5 mainly include symptomatic therapy, glucocorticoid and immunosuppressive therapy. 1. Symptomatic therapy: mainly protein-lowering and antihypertensive therapy, which is suitable for patients with simple lupus nephritis type 5 with non-nephrotic level proteinuria. For example, angiotensin-converting enzyme inhibitor (ACEI) or angiotensin II receptor antagonist (ARB) can be used to reduce urinary protein and blood pressure, and commonly used drugs such as enalapril and timosartan. 2. Glucocorticoid and immunosuppressant therapy: patients need to decide whether to undergo glucocorticoid and immunosuppressant therapy according to extra-renal manifestations. If the proteinuria of patients with lupus nephritis type 5 reaches the level of nephropathy, glucocorticoid combined with immunosuppressant therapy is needed, such as prednisone combined with cyclophosphamide or merti-macrolide, cyclosporine or tacrolimus. Patients with lupus nephritis type 5 are advised to go to the relevant departments of the hospital in time, under the guidance of professional doctors, improve the relevant examinations and receive standardized treatment, and the drugs should be used according to the doctor’s instructions, do not self-medication.