Leukorrhea have pus ball need according to the infection of specific pathogens medication, if for trichomonas infection, can use metronidazole and tinidazole; if for candida infection, can use clotrimazole; if for bacterial infection, can use metronidazole, clindamycin and so on. Pus ball in the leukorrhea indicates that there is a pathogen infection, but it is not certain which pathogen is specific, and further examination is needed to clarify. Common pathogens are bacteria, Trichomonas vaginalis and Candida. Trichomonas vaginalis can be treated with metronidazole or tinidazole vaginal tablets. For Candida infection, you can use clotrimazole vaginal suppositories; for bacterial infection, you can use metronidazole or clindamycin and other drugs for treatment. When the patient’s leukorrhea suggests that there is a pathogen infection, can not blindly self-medication, need to be further examination and then follow the doctor’s instructions for medication.