The treatment of chronic renal failure mainly includes 4 aspects: 1. treatment of primary diseases, such as diabetes, hypertension and connective tissue disease. 2. delaying further deterioration of renal function, mainly in the early stage of renal failure, including low protein diet plus alpha-keto acid therapy, control of systemic blood pressure and intrarenal pressure, with ACEI class and ARB class antihypertensive drugs as the main treatment. When the blood creatinine is greater than 350 μmol/L, the use of ACEI and ARB class drugs needs to be cautious.3. Treatment of complications, mainly the correction of water, electrolyte and acid-base balance disorders, treatment of anemia, treatment of calcium and phosphorus imbalance and renal bone disease, and prevention and treatment of cardiovascular system complications.4. Renal replacement therapy, currently there are three ways to choose: hemodialysis, peritoneal dialysis and kidney transplantation. Hemodialysis needs to be performed in the hospital, and the treatment is 2-3 times a week for 4-5 hours each time. Peritoneal dialysis is performed at home by patients themselves and requires changing the peritoneal dialysis solution 3-4 times a day for about half an hour each time. Kidney transplants can be inter-relative kidney donations or cadaveric kidney donations. These three alternative treatment modalities can be interchanged and patients can survive for more than 10-20 years.