The second day after drinking too much wine stomach upset, this situation is considered alcohol damage to the gastric mucosa, in addition to also cause gastric peristaltic dysfunction. These two conditions can be regulated by the following methods: First, on the second day you can drink thin rice or millet porridge and other liquid light food, which has a protective effect on the repair of the gastric mucosa, do not eat spicy, fried and other stimulating food. Second, if the effect of dietary adjustment is not good, you can consider using medication. Commonly used drugs are lansoprazole plus rehabilitation of new liquid or colloidal bismuth pectin. Generally this damage can be recovered in 3-5 days, and the medication will speed up the recovery of its mucous membrane, which will relieve stomach difficulty more quickly. Third, the stomach upset after drinking too much wine, but also to exclude alcohol damage to the liver, if more serious, it is recommended to go to the hospital to do gastroscopy, while blood tests liver function to exclude the degree of damage.