Small dark dots that can be seen in front of the eye are usually vitreous or retinal disease. Degeneration, hemorrhage, and inflammation within the vitreous and localized degeneration and hemorrhage in the retina may manifest as a dark spot in front of the eye. If this is present, fundus and ultrasound should be performed as soon as possible to clarify the severity of the disease. The location of retinal degeneration may be in the peripheral retina or in the central part of the retina. Peripheral retinal disease is easily missed, but may be an important cause of other serious eye diseases. Clinical manifestations are fixed black spots in front of the eyes, most of which have insignificant effects on vision, but once complications such as retinal fissures and retinal detachment occur, patients will experience enlarged black spots, fixed dark shadows, invasion of the macula, and significant loss of vision. Early treatment is required. Smaller fissures can be lasered, while larger ones require surgical repositioning.