Increased airway resistance in children may be related to bronchospasm, oral leukotriene modifiers such as montelukast, or antihistamines such as loratadine. Due to inflammatory stimulation, allergy and other factors, which cause bronchospasm, inflammatory swelling of the wall, mucus plug formation and airway remodeling, the child’s airway resistance increases, and symptoms such as dyspnea and wheezing appear. 1. Leukotriene modulators: such as montelukast, can reduce capillary permeability, inhibit airway hyperreactivity, relieve bronchospasm and reduce airway resistance. 2. Antihistamines: such as loratadine, cetirizine, etc., by reducing the release of histamine in the allergic reaction, avoiding capillary dilatation, increased permeability, reducing smooth muscle spasm, reducing mucus secretion, and reducing airway resistance. Children with increased airway resistance are advised to seek prompt medical attention and treatment. All of the above medications should be used under the guidance of a doctor, avoid self-medication.