Surgical thread rejection reaction wound has a hole may be suture level alignment is not good, incision local infection, local foreign body and other reasons. 1. Poor suture level alignment: a hole in the wound in response to surgical thread rejection may be caused by poor suture level alignment, resulting in poor healing of the incision, leading to a reduction in the speed of repair of local tissues, resulting in a hole in the wound. 2. Local infection of the incision: usually due to improper postoperative care of the patient may cause local infection of the incision, the infection will cause edema, oozing, pus in the surrounding tissue, resulting in a hole in the wound. 3. Local foreign body: surgical thread rejection reaction wound with a hole may also be localized in the wound with a foreign body, if the wound with a foreign body, will lead to repeated proliferation of local granulation tissue, affecting the wound healing, resulting in a hole in the wound. It is recommended that patients find a hole in the wound to go to the hospital in a timely manner, under the guidance of the doctor to standardize the treatment, and pay attention to the postoperative period to the hospital for re-examination.