Dwarfism does not necessarily require growth hormone, but the vast majority of children need growth hormone replacement therapy if they wish to grow taller. For example, in children with growth hormone deficiency, the incidence of which is currently 1/8,000, the annual growth rate of such children may be less than 5 cm if they do not undergo growth hormone replacement therapy, but if they are given growth hormone interventions, their annual growth rate may grow to 10-12 cm. At present, there are no oral preparations for growth hormone in the world, and the commonly used ones are mainly taken as subcutaneous injections. There are subcutaneous injections of aqueous, powdered, and long-acting agents. Powdered and aqueous agents are usually injected daily, while long-acting agents are given once a week. In the past, it was thought that growth hormone should be discontinued after puberty, but the current view is that patients with growth hormone deficiency still need to be treated with a small dose of growth hormone after puberty, and the drug should be used for the rest of their lives, because these children have some abnormalities of lipid metabolism in adulthood, and they are prone to coronary artery disease, which affects the lifespan of human beings. In addition, there are some idiopathic shortness, as well as Turner syndrome, Prader-Willi syndrome, these children can use growth hormone, but must be excluded from some oncological diseases or hematologic diseases, if there is no problem, can be growth hormone treatment.