Stem cell transplantation can treat liver cirrhosis by directly differentiating into hepatocytes, promoting hepatocyte regeneration and reducing liver fibrosis. 1. Direct differentiation into hepatocytes: after stem cells are transplanted into human liver, they can be differentiated into hepatocytes due to the microenvironment of liver injury, and the newborn hepatocytes are conducive to the gradual recovery of liver function. 2. Promote liver cell regeneration: due to the interaction between different cells, the transplanted stem cells can also activate hepatic stem cells in the liver, which can promote the regeneration of liver cells and further restore liver function. 3. Reduce liver fibrosis: liver fibrosis is more obvious in cirrhosis patients with excessive deposition of extracellular matrix, transplanted stem cells can degrade the excessive deposition of extracellular matrix and reduce liver fibrosis. Stem cell transplantation is currently not a recognized treatment method, there are certain unknown safety, effectiveness, etc. It is recommended that patients under the guidance of the doctor for targeted individualized treatment.