Patients and family members often ask us in the clinic, once they have done hemodialysis, they cannot withdraw from it, will it become an addiction? In fact, hemodialysis is the main treatment for end-stage renal disease uremic patients to survive for a long time, and it is by no means an addiction. To understand this issue, one has to understand what is chronic renal insufficiency uremic syndrome. Various primary and secondary kidney diseases that are not treated in a timely manner and progressive development can cause chronic renal insufficiency, and continue to develop to the uremic phase, when the main purpose of drug (including Western and Chinese medicine) treatment are two. The first is to protect the residual kidney function; the second is to treat the complications of uremia and protect the function of other organs. As the residual kidney function can no longer meet the normal needs of the human body, and it is difficult to remedy the failing kidney function by medication alone, renal replacement therapy must be carried out, that is, hemodialysis is used to replace the human kidney to complete its function of excreting waste. Hemodialysis is a necessary alternative treatment for patients with chronic renal insufficiency uremia, not an addiction.