Pre-Acromegaly may cause symptoms of cramping. Pre-Acromegaly is characterized by unilateral or bilateral awkwardness and weakness in finger movements, followed by atrophy of the small muscles of the hands, which may take on an eagle’s claw shape in both hands, gradually extending to the forearm, upper arm, and scapular girdle muscle groups. There are often obvious muscle fasciculations in the affected areas. Because acromegaly affects the upper motor neurons, resulting in increased muscle tone, muscle throbbing and cramp-like symptoms can occur. With the current medical level, it is not possible to completely cure acromegaly, and the treatment of this disease usually focuses on slowing down the progression of the disease and improving the patient’s quality of life. Riluzole tablets and vitamins can be taken to partially improve the symptoms of acromegaly. Patients with acromegaly need early detection and treatment to prolong their life. It is recommended that patients under the guidance of professional doctors for standardized treatment.