Homozygous immune thrombocytopenia can be treated with glucocorticoids, injections of gammaglobulin, and the use of immunosuppressive agents. Homozygous immune thrombocytopenia is a hyperfunctional immune system thrombocytopenia, which is usually treated clinically with glucocorticoids such as prednisone, intravenous gammaglobulin, and the use of immunosuppressive agents. The main mechanism of the disease is immune intolerance, specifically manifested as excessive destruction of peripheral platelets, bone marrow platelet production disorder, the most common symptoms of skin and mucous membrane bleeding, if women will have excessive menstrual manifestations. If the acute onset of platelets below 10 × 10^9 / L level should be treated promptly, platelet transfusion can be carried out. Homozygous immune thrombocytopenia is recommended for standardized treatment as soon as possible, the above drugs need to be used under the guidance of a physician, avoid self-medication.