Crohn’s usually refers to Crohn’s disease, a chronic inflammatory disease of the intestines that can occur throughout the digestive tract. There is racial variability and familial aggregation of the disease, and humoral and cellular immunity are also associated with the disease. Crohn’s disease initial symptoms are not obvious, the course of the disease is long, abdominal pain is the most common symptom, mostly in the right lower abdomen or umbilical pain, defecation or anal defecation after relief; early onset of diarrhea can be intermittent, later turned persistent, abdominal mass, fistula formation and other symptoms, may be accompanied by fever, nutritional disorders and other systemic reactions. There is no specific treatment for this disease. Symptomatic therapy is usually used, and if anemia is present the affected person may be supplemented with vitamin B₁₂, folic acid, or a blood transfusion. In the presence of intestinal secondary infections, broad-spectrum antibiotics such as levofloxacin and metronidazole may be used. Mesalazine, prednisone, and ustekinumab are also available and are effective in controlling active symptoms. The above medicines are for reference only, and specific dosage and usage should follow medical advice. The appearance of Crohn’s disease should be timely medical treatment, follow the doctor’s instructions, do not blindly use drugs.