Patients with bilateral carotid atherosclerosis combined with plaque should preferably use 1~2 kinds of antiplatelet drugs along with regular oral statin lipid-lowering drugs. 1. Statin lipid-lowering drugs: commonly used simvastatin, atorvastatin calcium and so on. Its role is to reduce the formation of lipid plaque by lowering blood lipids, in addition, statin for stabilizing plaque, reduce the effect of plaque rupture is worthy of affirmation, is one of the basic drugs for atherosclerosis. 2. Antiplatelet drugs: For those who already have plaque formation, the application of antiplatelet drugs can reduce the risk of thrombosis within the plaque. Commonly used drugs are non-steroidal anti-inflammatory drugs (such as aspirin, etc.), P2Y12 receptor antagonists (such as clopidogrel, etc.). The above drugs should be taken under the guidance of a doctor, and should not be used blindly on their own.