Cirrhosis of the liver for four years has been taking antiviral drugs, may not be completely cured, which is irreversible disease, but active treatment, generally can control the disease further progress. If the cirrhosis caused by viral infection, such as hepatitis B virus, in four years has been taking antiviral drugs, such as entecavir, lamivudine and so on also can not be cured. Cirrhosis is generally an irreversible disease, and the application of antiviral drugs can only alleviate the condition. Cirrhosis is a chronic progressive disease, liver damage is usually chronic, progressive, diffuse, patients usually have hepatocyte degeneration and necrosis, liver fibrosis and other basic pathological features, the course of the disease can be several years or even longer. In the advanced stage of cirrhosis, the condition will be aggravated, and complications such as hepatic encephalopathy and esophageal varices rupture and bleeding may occur. Cirrhosis patients are advised to take medication as prescribed by their doctors and not to take medication on their own.