Low-density thyroid lesions are specific descriptions of thyroid masses under ultrasound conditions, which can be followed up and observed according to the progress of the disease or treated with surgery as well as radiotherapy and chemotherapy, and it is recommended to follow the doctor’s instructions for treatment. If the patient has no obvious clinical symptoms, or the nodule is small and benign, no special treatment is needed for the time being, and regular checkups in the hospital will be enough. If the nodule is large or malignant, surgery should be adopted for treatment. If the nodule is diagnosed as malignant, radiotherapy or chemotherapy may also be needed after surgery to improve the efficacy of the treatment. Suffering from low-density thyroid nodules should be promptly examined in regular public hospitals for a clear diagnosis, and treatment should be carried out under the guidance of doctors.