There is no specific time for the development of UTI in PAPN, it is mostly related to the patient’s own condition and the severity of the disease, less than half a year, more than a lifetime may not develop to UTI. If the patient is a mild thylakoid glomerulonephritis, the pathological reaction is relatively mild, may only appear mild proteinuria or have a slight urinary occult blood, this situation can be controlled through timely treatment, most patients may not develop to uremia. If it is a severe case of thylakoid nephritis, patients who are not treated in time or improperly treated will cause a series of complications, including a large amount of urinary protein, renal parenchyma destruction, decline in renal function, etc. The glomeruli may have proliferation of hardening, fibrosis, etc., which will lead to loss of renal function, and the fastest time is half a year, which will lead to the transformation of the disease into uremia. If you are suffering from proliferative nephritis, you should actively cooperate with your doctor to avoid the deterioration of the condition and accelerate the development of the disease leading to uremia.