The appearance of a cold after a cold has been pus nose, indicating that the cold is caused by a bacterial infection of the nasal cavity, need to use antibiotics for treatment. For example, penicillin, if there is no allergic condition, you can use amoxicillin, or amoxicillin clavulanate potassium to anti-inflammatory, for purulent infection is more effective. If there is some allergy to penicillin, you can use cephalosporin antibiotics for treatment, such as cefixime, cefaclor, cefradine, cefadroxil or cefadroxil, which are more effective. If allergies to cephalosporins also exist, adults can take oral levofloxacin or roxithromycin to reduce inflammation. In the case of children, azithromycin can be taken orally for treatment. These kinds of drugs have a certain stomach stimulating effect, must be taken after meals, the effect is better. Usually in the morning and at night, you need to use light warm salt water to clean the nasal cavity, which is also more effective in relieving the phenomenon of having pus nasal discharge all the time.