Hand numbness should first find the cause of the disease, according to the cause of the treatment, commonly used drugs are vitamin B1, methylcobalamin, Hua Tuo Zaizao Pill and so on. Hand numbness is common in cerebrovascular disease, peripheral neuropathy and cervical spondylosis. 1. Vitamin B1: It is a water-soluble vitamin, which has the function of maintaining digestive nerve and sugar metabolism, and is used in vitamin B1 deficiency and peripheral neuritis. 2. Methylcobalamin: an endogenous coenzyme B12, has the effect of nourishing the nerves, and can be used in the treatment of anemia and peripheral neuritis. 3. Hua Tuo Zaizaoyuan: it has the functions of activating blood circulation and removing blood stasis, clearing channels and relieving pain (dredging channels and collaterals, relieving pain) and resolving phlegm and promoting circulation of qi, and is used in the treatment of post-stroke, numbness of the limbs, crookedness of the eyes and mouth, and speech impediment. If there is any discomfort, it is recommended that patients go to the neurology department of regular hospitals for consultation and treatment in a timely manner, and should not blindly take medication on their own to avoid delaying or aggravating the condition.