Low activated partial thromboplastin generally suggests that the organism is in a hypercoagulable state. Activated partial thromboplastin time (APTT), is an important and sensitive indicator of the screening of endogenous coagulation system of the organism. APTT is the time required to activate coagulation factor D.E. by contacting factor activator as a reagent, replacing PF3 with partial thromboplastin (ceruloplasmin), and observing plasma coagulation by the addition of calcium during a standard in vitro time. Its normal values are generally 26-36 seconds for the instrumental method and 32-43 seconds for the manual method. Generally low activated partial thromboplastin time is seen in thrombotic disorders such as cerebrovascular lesions, pulmonary infarction, myocardial infarction, unstable angina pectoris, diabetes mellitus with vasculopathy, and deep vein thrombosis. Low activated partial thromboplastin time can also be caused by hypertensive syndrome of pregnancy and nephrotic syndrome. If you have a low activated partial thromboplastin time, you need to consult a doctor for further examination to clarify the cause of the disease and then carry out targeted treatment.