The stomach is very bloated against the difficult may be due to physiological causes, but also may be due to gastritis, gastric ulcer, gastrointestinal dysfunction and other pathological causes. Proton pump inhibitor drugs and gastric stimulating drugs can be chosen for treatment. 1. Physiological causes: may be due to excessive stress, unhygienic diet, irregular lifestyle, eating too much greasy and other reasons, generally do not need special treatment, pay attention to regulating stress, healthy diet can be relieved. 2. Pathologic causes: (1) Gastritis, gastric ulcer: stress, Helicobacter pylori infection and other factors can lead to gastritis and gastric ulcer, gastrointestinal, stomach pain, nausea, vomiting and other symptoms. Acid suppressants such as omeprazole can be applied for treatment. If Helicobacter pylori infection exists, eradication treatment can be carried out by the quadruple method, i.e. one proton pump inhibitor such as omeprazole + one bismuth such as colloidal bismuth + two antibiotics such as amoxicillin and clarithromycin. (2) Gastrointestinal dysfunction: weakened gastrointestinal dynamics will lead to difficulty in absorbing and expelling gas from the stomach, thus causing the feeling of bloating. It is recommended that patients use gastric motivation drugs for treatment, common domperidone tablets, etc., to promote gastrointestinal motivation, strengthen the role of gastric peristalsis. It is recommended that patients whose stomachs are very distended and difficult to top go to the hospital in a timely manner to avoid delaying their condition.