The vague stabbing pain in the middle of both breasts is a painful sensation behind the sternum and is associated with the following diseases: firstly, injury to the sternum or ribs caused by trauma, or some problems with the rib nerve, which can cause a stabbing sensation. The pain is usually prolonged for several hours to several days, with pins and needles sensation being more common. It is related to activity, and doing stretching exercises may cause the pain to increase. Secondly, coronary artery disease should be suspected. If vague pain in the middle of the sternum occurs after emotional excitement or activity, coronary artery disease is not excluded, and patients need to improve coronary CT and other tests to clarify the diagnosis. Furthermore, some esophageal diseases, such as suffering from reflux esophagitis, can also cause painful sensations in this area.