Newborns with white spots on the bottom of the left eye may be related to preterm birth and high concentration of oxygen, congenital cataract, metastatic endophthalmitis and other factors, which are analyzed as follows: 1. Preterm birth with high concentration of oxygen intake: If the newborn has a white spot on the bottom of the left eye and belongs to a preterm baby with a history of oxygen intake, it may lead to the development of retinopathy. 2. Congenital cataract: If a newborn is born with a white spot on the bottom of the left eye, it may be due to congenital factors, such as congenital cataract. 3. Metastatic endophthalmitis: If the newborn is not only accompanied by the above conditions, but also has a lot of eye boogers, eyelid swelling and other undesirable conditions, it is considered to be related to metastatic endophthalmitis. Newborns with white spots on the bottom of the left eye may have other factors, it is recommended to go to the hospital in time for relevant examinations, to clarify the cause of the disease and then actively treat the symptoms.