Painful sinking sensation in the buttocks is mainly considered to be inflammation in the buttocks, including aseptic inflammation as well as infectious inflammation. Aseptic inflammation is common due to injury, strain, poor stimulation, and poor blood circulation, resulting in edema, congestion, and inflammatory exudation in the soft tissues of the buttocks and painful drop. Infectious inflammation is common due to secondary infection of the skin of the buttocks, or secondary infection of perianal hemorrhoids or perianal abscesses, which can also produce a large number of inflammatory cell infiltrates and even abscesses accordingly, thus stimulating the nerves around the buttocks and producing painful sensation of falling. In this case, it is recommended to go to the hospital for examination and take appropriate treatment after clear diagnosis.