Whether renal function test uric acid 505umol/L is serious needs to be assessed in combination with whether it is combined with renal disease and other factors. If the patient does not have renal disease and other complications, after adjusting lifestyle, uric acid may decline, at this time is usually not serious; if the combination of renal disease and other complications, renal function continues to be impaired, renal failure may occur, at this time is more serious. Uric acid is the end product of purine metabolism, under daily diet, non-same day twice fasting blood uric acid level > 420 μmol / L can be diagnosed as hyperuricemia. Urate forms crystals that are deposited in a variety of tissues, including the kidneys and synovium of joints, causing tissue damage. Therefore, uric acid 505 μmol/L indicates elevated uric acid. If the patient does not have obvious symptoms and is not combined with other complications, after controlling diet and increasing water intake, and medication if necessary, the uric acid level may decrease, and this condition is usually not serious; if the patient develops gouty nephropathy, uric acid nephrolithiasis, and other complications, the uric acid level, if it continues to rise and damage the kidneys, may develop renal failure, which is more serious at this time. If the patient has elevated uric acid, it is recommended to go to the regular hospital in time, under the guidance of the doctor to standardize the treatment.