Taking sakubutra valsartan can be temporarily observed, can also be appropriate to give cough medication orally, the seriousness of the condition to follow the doctor’s instructions to reduce or stop the drug. Sacubitril valsartan is mainly used in the treatment of heart failure, some patients after taking the drug can appear coughing adverse reactions, mild symptoms do not need to stop, observe the changes in the condition, the symptoms can gradually improve. After taking the drug cough obvious patients, can also be appropriate to give cough medicine oral, such as compound licorice tablets, can be appropriate to relieve the symptoms of cough. For patients with particularly severe coughs, reduce the dose of the drug and stop the drug if necessary. Sacubitril valsartan can lead to hypotension, cough and other adverse reactions, for the drug component allergy, are taking ACEI, ACEI-related angioedema, severe hepatic and renal impairment, cholestatic cirrhosis, patients in the middle and late stages of pregnancy is prohibited. Sacubitril valsartan should be used under the guidance of a physician, and the occurrence of adverse reactions should be communicated with the doctor in a timely manner and treated under the guidance of the physician.