The treatment of degenerative osteoarthritis of the knee joint for patients mainly includes weight control, resistance training, medication and physical therapy, as follows: First, weight control: strict weight control to reduce the pressure on the knee joint can improve degenerative changes, while patients should try to reduce excessive weight bearing on the knee joint and walking distance, the patient’s pain symptoms can be significantly improved. Second, resistance training: strengthen the strength and intensity of the muscles around the knee joint, mainly resistance training, can assist elastic bands and other tools, so that the stability of the knee joint can be significantly improved, but also can slow down the speed of degenerative changes, inhibit clinical symptoms. Third, medication: Treatment with non-steroidal anti-inflammatory drugs, such as celecoxib, loxoprofen sodium, and pautazone, can inhibit joint inflammation and reduce joint pain. Fourth, physical therapy: physical therapy, such as ultra-short wave therapy, microwave therapy, far-infrared therapy, can accelerate the inflammation and improve joint blood circulation.