Whether cytokeratin 19 fragment high 0.6 is serious or not is related to the reason that causes the indicator to be elevated, if the indicator is high due to malignant tumor, it is generally more serious, if the indicator is elevated due to non-tumor diseases, it is generally not serious. Cytokeratin 19 fragment is a tumor marker that can be detected in the blood to assist in the diagnosis of malignant diseases. If the index is elevated, it is generally considered to be the cause of malignant tumors such as lung cancer, bladder cancer, or possibly non-tumor causes such as pneumonia and bronchitis. Lung cancer, bladder cancer and other diseases that develop into middle and late stages may often cause elevated markers, and the survival time of patients in middle and late stages is significantly shorter, so it is more serious. On the other hand, inflammatory non-tumor diseases such as pneumonia and esophagitis may be cured through active treatment such as anti-infection, and the cytokeratin 19 fragment is usually normalized after cured, so it is not serious.