Mycoplasma antibody 1:80 is suggestive of Mycoplasma positivity, indicating a possible infection. However, the type of antibody needs to be clarified and treatment is required if it is IgM antibody positive. There are 16 types of mycoplasma associated with humans, and among them, the types of mycoplasma that can cause human illness are Mycoplasma pneumoniae, Mycoplasma genitalium, Mycoplasma spermatophilum, and Ureaplasma urealyticum. In the case of Mycoplasma pneumoniae, for example, an IgM-positive antibody suggests the possibility of a recent infection, which indicates that the body is in a state of mycoplasma infestation and requires timely treatment. For Mycoplasma pneumoniae infection, quinolone antibiotics such as Roxithromycin, Clarithromycin and Sparfloxacin can be used, and the doctor should be consulted in order to avoid drug-resistant strains of Mycoplasma pneumoniae being induced by random medication. If the type of antibody is IgG-positive, it suggests a previous infection with a related mycoplasma. In this case, observation can be continued and drug treatment is usually not required. If there is a combination of other symptoms and self-consciousness, it is necessary to be admitted to the hospital for further analysis and to seek medical help in a timely manner.